Rhythmic neuronal activity reflects the coordination and interactions of networks of neurons during complex cognitive processes and behaviour. Accordingly, many psychiatric disorders are associated with impaired neural synchrony.
We use specialized 'tetrode' electrodes to record simultaneously from large groups of neurons, measuring synchrony of network activities in anatomically and functionally related circuits, both during normal behaviour and in models of diseases like schizophrenia, Down syndrome and Alzheimer's Disease.
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