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The roles played by ion channels, neurotransmitter and neuromodulatory receptors and a wide range of associated proteins are fundamental to our understanding of brain function. Investigations into the molecular mechanisms by which opioid receptors, AMPA and NMDA receptor expression are controlled have been fundamental to our understanding of the physiological changes seen in neuronal plasticity which underpin learning and addiction while research into the mechanisms of action of Ca2+, Na+ and K+ channels have revealed how multiple ion fluxes control neuronal activity.

This area contributes to the wider Neuroscience research theme within the School of Physiology and Pharmacology.