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Publication - Professor Eamonn Kelly

    How the complex pharmacology of the fentanyls contributes to their lethality.

    Citation

    Henderson, G, Kelly, E & Gill, H, 2019, ‘How the complex pharmacology of the fentanyls contributes to their lethality.’. Addiction.

    Abstract

    Fentanyls as a class of drug have pharmacological properties that make them more likely to lead to overdose than other opioids. In addition to their high potency and rapid onset of action these drugs induce respiratory muscle stiffness making it difficult to breath, are less sensitive than heroin to naloxone reversal and may show reduced cross tolerance to other opioids.

    Full details in the University publications repository