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Dr Amelia Burroughs

Dr Amelia Burroughs

Dr Amelia Burroughs
PhD

Honorary Research Associate

Area of research

How variations in Purkinje cell signalling contribute to motor behaviour.

Office F41
Merchant Venturers Building,
Woodland Road, Clifton BS8 1UB
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+44 (0) 117 331 2291

Summary

Purkinje cells are the principal neuron of the cerebellum, a brain region critically implicated in motor coordination, and the only neuronal type to project out from the cerebellar cortex. They are unique in that they fire two distinct types of action potentials: simple (stereotypical) and complex spikes. Unlike stereotypical action potentials, the waveform of the complex spike is not an all-or-none response. Using in vivo electrophysiology, I aim to elucidate the significance of small variations in the complex spike signal with regards to motor behaviour.

Biography

Before starting my PhD in Neural Dynamics, I obtained a BSc in Neuroscience from University College London (UCL). My final year project combined high-resolution microscopy and data analysis techniques to understand the spatial arrangement of synapses onto the Purkinje cell and local interneurons of the cerebellum. 

Memberships

Organisations

Department of Computer Science

Recent publications

View complete publications list in the University of Bristol publications system

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