Research activities in the laboratory focus on investigating the replication and pathogenesis of Dengue virus and SARS coronavirus with an overall aim of developing improved antiviral agents and vaccines.
The dengue viruses are spread by mosquitoes and infect up to 50 million individuals annually in sub-tropical and tropical regions of the world. Dengue disease has emerged as the most important arthropod-borne viral disease of humans. Dengue virus infection generally results in dengue fever, a debilitating but self limited febrile disease. However, complications may arise, leading to the potentially fatal dengue haemorrhagic fever/dengue shock syndromes (DHF/DSS). Despite ...
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