Molecular mechanisms of host-pathogen interactions
The virulence of pathogenic bacteria relies on their ability to induce signals within host cells to alter their behaviour. This can involve surface expression of proteins, secretion of toxins or, in some of the most interesting examples, direct transfer of proteins by bacteria into host cells. My group has mainly focused on the molecular mechanisms underlying the cross-talk between pathogenic bacteria such as Salmonella and enteropathogenic E. coli (EPEC) and epithelial cells. Through collaborations we have also extended our research interests to encompass other pathogns including Campylobacter, Streptococci and EHEC. Specific areas of ...
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