Dr Andrew Davidson

Research summary

Research activities in the laboratory focus on investigating the replication and pathogenesis of Dengue virus and coronaviruses (including MERS-CoV and feline coronavirus). High-throughput transcriptomic and proteomic approaches are being used to increase our understanding of the virus host interaction with an overall aim of developing improved antiviral agents, vaccines and diagnostics. Synthetic biology approaches are being used to produce a novel platform for future vaccine delivery. 

Dengue virus

The dengue viruses are spread by mosquitoes and infect up to 390 million individuals annually in sub-tropical and tropical regions of the world. Dengue disease has emerged as the most important ...

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Recent publications

• Li, XF, Dong, HL, Wang, HJ, Huang, XY, Qiu, YF, Ji, X, Ye, Q, Li, C, Liu, Y, Deng, YQ, Jiang, T, Cheng, G, Zhang, FC, Davidson, AD, Song, YJ, Shi, PY & Qin, CF, 2018, ‘Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone’. Nature Communications, vol 9.
• Naiyer, MM, Cassidy, SA, Magri, A, Cowton, V, Chen, K, Mansour, S, Kranidioti, H, Mbirbindi, B, Rettman, P, Harris, S, Fanning, LJ, Mulder, A, Claas, FHJ, Davidson, AD, Patel, AH, Purbhoo, MA & Khakoo, SI, 2017, ‘KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C’. Science Immunology, vol 2.

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View complete publications list in the University of Bristol publications system