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Professor Julian Gough
Professor Julian Gough
MSc(Bristol), PhD(Cantab)
Research Fellow in Computer Science
Professor of Bioinformatics
Research summary
Research interests
http://bioinformatics.bris.ac.uk/research.php
http://bioinformatics.bris.ac.uk/people/julian_gough.php
- Reference species tree of sequence life.
- The evolution of the protein repertoire
- Comparative genomics
- Biological sequence analysis
- 3D protein structure
- The SUPERFAMILY database
- The FANTOM mouse and human projects
- Hidden Markov models (book chapter)
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Biography
Background
- Degree in joint hon.s Mathematics and Physics from the University of Bristol
- PhD from Cambridge University with Cyrus Chothia in Theoretical and Computational Biology
- Research Associate for the MRC Laboratory of Molecular Biology in Cambridge
- PMMB fellow at Stanford University with Michael Levitt in Computational and Structural Biology
- RIKEN Scientist with the GER group at the Genome Sciences Centre in Tokyo
- Associate Professor at Tokyo Medical and Dental University
- Visiting scientist at the Pasteur Institute in Paris
- Reader of Bioinformatics at the University of Bristol
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Recent publications
- Shihab, HA, Gough, J, Cooper, DN, Day, INM & Gaunt, TR 2013, Predicting the functional consequences of cancer-associated amino acid substitutions. Bioinformatics (Oxford, England), vol 29., pp. 1504-10
- Radivojac, P, Clark, WT, Oron, TR, Schnoes, AM, Wittkop, T, Sokolov, A, Graim, K, Funk, C, Verspoor, K, Ben-Hur, A, Pandey, G, Yunes, JM, Talwalkar, AS, Repo, S, Souza, ML, Piovesan, D, Casadio, R, Wang, Z, Cheng, J, Fang, H, Gough, J, Koskinen, P, Törönen, P, Nokso-Koivisto, J, Holm, L, Cozzetto, D, Buchan, DWA, Bryson, K, Jones, DT, Limaye, B, Inamdar, H, Datta, A, Manjari, SK, Joshi, R, Chitale, M, Kihara, D, Lisewski, AM, Erdin, S, Venner, E, Lichtarge, O, Rentzsch, R, Yang, H, Romero, AE, Bhat, P, Paccanaro, A, Hamp, T, Kaßner, R, Seemayer, S, Vicedo, E, Schaefer, C, Achten, D, Auer, F, Boehm, A, Braun, T, Hecht, M, Heron, M, Hönigschmid, P, Hopf, TA, Kaufmann, S, Kiening, M, Krompass, D, Landerer, C, Mahlich, Y, Roos, M, Björne, J, Salakoski, T, Wong, A, Shatkay, H, Gatzmann, F, Sommer, I, Wass, MN, Sternberg, MJE, Skunca, N, Supek, F, Bošnjak, M, Panov, P, Džeroski, S, Smuc, T, Kourmpetis, YAI, Dijk, ADJv, Braak, CJFT, Zhou, Y, Gong, Q, Dong, X, Tian, W, Falda, M, Fontana, P, Lavezzo, E, Camillo, BD, Toppo, S, Lan, L, Djuric, N, Guo, Y, Vucetic, S, Bairoch, A, Linial, M, Babbitt, PC, Brenner, SE, Orengo, C, Rost, B, Mooney, SD & Friedberg, I 2013, A large-scale evaluation of computational protein function prediction. Nature Methods, vol 10., pp. 221-7
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