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Dr Nicholas Claydon

Dr Nicholas Claydon

Dr Nicholas Claydon
B.D.S., M.Sc.D.(Wales), Ph.D.(Bristol)

Clinical Lecturer

Area of research

Evaluation of oral healthcare products, soft and hard tissue regeneration and implantology

Lower Maudlin Street,
Bristol, BS1 2LY
(See a map)

+44 (0) 117 342 4417
+44 (0) 117 342 4410


The Clinical Trials Unit is in the international arena of research with regards to toothwear (erosion, attrition, abrasion and abfraction), tooth bleaching, tooth staining, dentine hypersensitivity, prevention of plaque and gingivitis and treatment of diseases of the periodontium, and soft and hard tissue regeneration in periodontology and implantology . The studies are carried out both within the Clinical Trials Unit at the Bristol Dental School in dedicated laboratories and clinical environment, and in General Dental Practice in the UK. Studies are often initially conducted in vitro before moving into in situ and in vivo models. The research group has developed an ethically approved in situ model using human teeth to assess, in particular, the erosive properties of acidic soft drinks, the abrasive and erosive effects of oral healthcare products and their synergistic effect with each other, in order to help manage clinical toothwear which is the fourth most common condition in dentistry after caries, periodontal disease and trauma. Further these models allow occlusion of dentine tubules to be assessed in order to reduce the pain of dentine hypersensitivity experienced by at least 15% of the population worldwide. Other areas of active research involve studies into bioglasses, dental implants, bone regenerative materials and pain reduction when performing oral local anaesthesia.

The majority of the research is supported by international industrial funding from the UK, Europe, Switzerland and the US as well as external grants such as EU monies.


Nick Claydon is a graduate of the University of Wales College of Medicine (Cardiff, 1986) and is registered to the General Dental Council. He attained his MScD in Periodontal research at the University of Wales and his PhD from the University of Bristol entitled, Development and Application of Methods to Study Plaque Control by Dental Health Products. He was accredited as a specialist in Periodontics by the General Dental Council in 2000. Nick is a member of the Royal College of Surgeons of England, is a Faculty member of the British Society of Periodontology and a Fellow of the Higher Education Academy. He is currently a Clinical Research Fellow and Lecturer at Bristol Dental School and in addition, is a Clinical Lecturer in Implantology at Cardiff Dental School.

His research interests include developing research methodologies, periodontal conditions, bone augmentation and peri-implant lesions, the scientific evaluation of oral health care products, tooth wear, dentine hypersensitivity and tooth whitening. He has conducted more than 70 clinical research studies and has published over 40 papers in peer-reviewed journals in these fields of interest. Nick lectures in the national and international forum and is a reviewer for high impact dental journals.

Nick founded a thriving dental practice in Cardiff in 1997. In 2010, he established his state of the art dental practice at The Pines in Whitchurch, Cardiff. He has developed a national reputation for aesthetic treatment of complex restorative cases involving periodontal, implant and prosthodontic treatment. Nick’s innovative approach to dentistry has lead to the adoption and implementation of the cutting edge technologies. Nick lectures widely on his research and practice concepts.

He contributes to the periodontology, bone augmentation and peri- implantitis programmes in the Bristol and Cardiff Dental School Masters degrees for Periodontology and Implantology, as well as lecturing on the undergraduate dental program in Restorative Dentistry. He attends the Specialist Advisory Committee for Restorative Dentistry for the Royal College of Surgeons of England as well as being an active member of the British Society of Periodontology, the Association of Dental Implantology, a member of the International Team of Implantology.

Nick utilises his valuable teaching experience as mentor both within and external to the Practice Group, managing complex restorative, periodontal and implant cases for dentists. 


  • Clinical Trials
  • Plaque regrowth
  • erosion
  • dentine hypersensitivity
  • research methodologies
  • toothbrushing efficacy
  • chemical plaque control
  • halitosis
  • staining



Bristol Dental School

Academic staff

Research groups

Recent publications

View complete publications list in the University of Bristol publications system

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