Professor Marianne Thoresen

Professor Marianne Thoresen
M.D., Ph.D.(Oslo)

Professor of Neonatal Neuroscience

Area of research

Physiology and neuroprotection of the newborn

Neonatology,
Level D, St Michael's Hospital BS2 8EG
(See a map)

Fax. +44 (0) 117 34 25751
Tel. +44 (0) 117 34 25607
marianne.thoresen@
bristol.ac.uk

Research summary

Worldwide, newborn infants suffer death or permanent brain damage caused by diseases arising before or around the time of birth. I do translational research aimed at developing effective treatment. By integrating my studies of normal physiological changes in many organ systems with pathological changed seen during disease, I have -together with my students - developed experimental models that mimic global hypoxic-ischemic injury and brain haemorrhage leading to permanent disability in children. The neuroprotective effect of cooling newborns first presented in these models led to international clinical trials where we documented the same neuroprotective effect in humans that were cooled and this ...

Recent publications

Lee-Kelland, R, Jary, S, Tonks, J, Cowan, F, Thoresen, M & Chakkarapani, E, 2019, ‘School-age outcomes of children without cerebral palsy cooled for neonatal hypoxic-ischaemic encephalopathy in 2008-2010’. Archives of Disease in Childhood: Fetal and Neonatal Edition.
El-Dib, M, Inder, TE, Chalak, LF, Thoresen, M & Gunn, AJ, 2019, ‘Should therapeutic hypothermia be offered to babies with mild neonatal encephalopathy in the first 6 h after birth?’. Paediatric Research.

Professor Marianne Thoresen