Professor Marianne Thoresen

Professor Marianne Thoresen
M.D., Ph.D.(Oslo)

Professor of Neonatal Neuroscience

Area of research

Physiology and neuroprotection of the newborn

Neonatology,
Level D, St Michael's Hospital BS2 8EG
(See a map)

Fax. +44 (0) 117 34 25751
Tel. +44 (0) 117 34 25607
marianne.thoresen@
bristol.ac.uk

Research summary

Worldwide, newborn infants suffer death or permanent brain damage caused by diseases arising before or around the time of birth. I do translational research aimed at developing effective treatment. By integrating my studies of normal physiological changes in many organ systems with pathological changed seen during disease, I have -together with my students - developed experimental models that mimic global hypoxic-ischemic injury and brain haemorrhage leading to permanent disability in children. The neuroprotective effect of cooling newborns first presented in these models led to international clinical trials where we documented the same neuroprotective effect in humans that were cooled and this ...

Recent publications

Van Bel, F, Hellstrom-Westas, L, Zimmermann, L, Buonocore, G, Murray, D, Saliba, E & Thoresen, M, 2018, ‘European Foundation for the Care of Newborn Infants (EFCNI): European Standards of Care for Newborn Health: Postnatal management of newborn infants with hypoxic ischaemic encephalopathy (HIE)’. in: European Foundation for the Care of Newborn Infants (EFCNI) : Postnatal management of newborn infants with hypoxic ischaemic encephalopathy (HIE)., pp. 34-56
Falck, M, Osredkar, D, Maes, E, Flatebø, T, Wood, T, Walløe, L, Sabir, H & Thoresen, M, 2018, ‘Hypothermia is Neuroprotective after Severe Hypoxic-Ischaemic Brain Injury in neonatal rats pre-exposed to PAM3CSK4’. Developmental Neuroscience.

Professor Marianne Thoresen