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Professor Marianne Thoresen


I trained as a physiotherapist. Treating children with cerebral palsy motivated me to study medicine. While a medical student I took a PhD on cerebral blood flow in the newborn infant. I was a postdoctoral fellow at the Karolinska Institute, Stockholm and then trained as a clinical paediatrician in Oslo. I became interested in cerebral protection from hypothermia in 1990 and was, in 1995, the first to show that post-hypoxic cooling could reduce brain damage in the newborn. I have investigated the mechanisms by which hypothermia protects the newborn brain and was one of the first to pilot the clinical use of hypothermia in babies when I moved to UK in 1998. I am currently working as a Consultant Neonatologist at St Michael's Hospital in Bristol.

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Key words

  • effect of temperature on the development of brain injury
  • cellular mechanisms of hypothermic neuroprotection
  • drugs and hypothermia
  • protective strategies against posthaemhorrhagic ventricular dilatation