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Brain Tumour Research Centre

The following people are in this group:

More about this group

Head of Centre

Dr Kathreena M Kurian

Approximately 7,000 patients in the UK develop primary brain cancer, but there are many more who develop secondary cancer within the brain from different primary sites around the body (such as breast and lung). One of the major problems with primary brain cancer is that it invades the brain widely as single cells and therefore can be difficult to completely remove by surgery. It also can develop resistance to traditional chemotherapy and therefore tumour relapse is common.

The Brain Tumour Research Centre aims to involve fully understanding each individual’s tumour according to what is driving the abnormal growth of that specific tumour. Then surgery and a range of therapies can be tailored to the individual, providing a personalised medicine approach.

We collaborate with a range of groups including Brain Tumour Research Charities, neuro-oncologists, neurosurgeons, neurologists and Bristol Genetics Laboratory. We are proud to have patient representation on our Brain Tumour Bank committee. The group cell lines recently featured on the cover of Nature Reviews Clinical Oncology 2012.

Our projects and collaborations include:

  • Studies into the molecular genetics and biomarkers of brain tumours
  • Abnormal pathways driving brain and spinal cord tumours
  • Neuroradiology studies using metabolite profiles with NMR to predict tumour behaviour 
  • Convection enhanced delivery to improve drug delivery to tumours among many other

Just published in the BMJ:  Early morning headache with vomiting in a 5 year old boy 

Head of Centre

kathreena.kurian@nbt.nhs.uk 

Department of Neuropathology,
Frenchay Hospital, Frenchay Park Road,
Bristol BS16 1LE

Secretary

Joanna.McTiernan@nbt.nhs.uk

Direct Dial: 0117 340 2381
Mobile: 07765 965659
Department: 0117 340 2385

Centre Manager

Hannah.Williams@nbt.nhs.uk

Research Registrar

Dr Harry Haynes

More details ...