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Dr Emily Williams

Dr Emily Williams

Dr Emily Williams
PhD, BSc (Hons)

Senior Research Associate

Biomedical Sciences Building,
University Walk, Bristol BS8 1TD
(See a map)

Research summary

Current research:

  • Developing an antibody drug conjugate for selective calcineurin inhibition of T-cells for the treatment of corticosteroid resistant autoimmune diseases.
  • Investigating the role of monocyte subsets in human inflammatory disease and response to synthetic glucocorticoid steroids.
  • Facilitating other research projects meeting the research objectives of the National Institute of Health Research (NIHR) Biomedical Research Centre (BRC) for Ophthalmology and the UNITE human ocular immunology consortium

 

 

Antibody-drug conjugate:

Building on our previous published research (https://www.pnas.org/content/112/13/4080) where we have discovered a key subset of immune cells that are not only key to ...

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Biography

I have a long-standing interest in the development and application of monoclonal antibodies for therapeutic application in both cancer and autoimmune disease. I completed a PhD with Prof. Mark Cragg (Antibody and Vaccine Group, University of Southampton) in 2010 studying the therapeutic efficacy of direct-targeting monoclonal antibodies (mAbs) towards the inhibitory Fcgamma-receptors in murine models of lymphoma. Following this, I undertook a post-doctoral position with Dr Juliet Gray (Antibody and Vaccine Group, University of Southampton), investigating therapeutic anti-tumour immunity in pre-clinical neuroblastoma models by combining immunomodulatory mAb targeting T-cells co-stimulatory and co-inhibitory molecules with peptide vaccination. Having spent several years ...

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Recent publications

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View complete publications list in the University of Bristol publications system

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