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Publication - Mr Ben Flynn

    The emerging importance of ultradian glucocorticoid rhythms within metabolic pathology

    Citation

    Flynn, BP, Conway-Campbell, BL & Lightman, SL, 2018, ‘The emerging importance of ultradian glucocorticoid rhythms within metabolic pathology’. Annales d'Endocrinologie, vol 79., pp. 112-114

    Abstract

    Glucocorticoid (GC) hormones play significant roles within homeostasis and the chrono-dynamics of their regulatory role has become increasingly recognised within dysregulated GC pathology, particularly with metabolic phenotypes. Within this article, we will discuss the relevance of the ultradian homeostatic rhythm, how its dysregulation effects glucocorticoid receptor and RNA polymeraseII recruitment and may play a significant role within aberrant metabolic action.

    Full details in the University publications repository