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Professor Athimalaipet Ramanan

Paediatric Rheumatology

My research in the area of paediatric rheumatology includes:

  • Randomised controlled trials of novel biological drugs in children with JIA associated uveitis. I am the Co-Chief Investigator of Sycamore Trial (RCT of adalimumab in JIA associated uveitis) funded by HTA/ARUK. I am also the Co-Chief Investigator of a trial of Tocilizumab in anti TNF refractory JIA associated uveitis.
  • Leading on new agents for management of refractory arthritis in collaboration with industry
  • Design and conduct studies in rare disease using novel study designs (Bayesian and Simon design)
  • Looking at diagnostic markers and new therapies for MAS or secondary HLH
  • Collaboration with colleagues in India on secondary HLH in Dengue fever
  • Basic science studies on understanding pathogenesis of lupus nephritis
  • Biomarkers in JIA and JIA associated uveitis.

Activities/Findings:

  • Associate Editor – Archives of Diseases in Childhood
  • Editorial Board – Rheumatology
  • Scientific Member, ARUK/MCRN Paediatric Rheumatology Clinical Studies Group
  • Associate Director of ARUK funded only Paediatric Experimental Arthritis Treatment Centre leading on JIA-Uveitis and Industry workstreams
  • Medical Advisor for National Rheumatoid Arthritis Society (NRAS) and National Ankylosing Spondylitis Society (NASS)
  • Research Advisor for RCPCH Paediatric Rheumatology CSAC.

Research keywords

  • Randomised controlled trials in paediatric rheumatology
  • Paediatric Uveitis
  • Immunomodulatory therapy
  • Trials of novel biological agents including using adaptive designs
  • Musculoskeletal problems in children
  • Kawasaki disease

Researchers