Professor Andrew Whitelaw

Research summary

Intraventricular haemorrhage (IVH) and hydrocephalus in premature babies. Ventricular lavage reduces brain injury and disability in posthaemorrhagic hydrocephalus by to remove toxic substances released by old blood (eg free iron and pro-inflammatory cytokines.

Hypoxic-ischaemic injury in babies born at full term. Total body hypothermia for neonatal hypoxic-ischaemic encephalopathy improved the odds of surviving without neurological impairment at 18 months. Since 1998 the 2 Bristol neonatal intensive care units have been pioneers in therapeutic cooling for babies.

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Recent publications

• , Cizmeci, MN, Khalili, N, Claessens, NH, Groenendaal, F, Liem, KD, Heep, A, Benavente-Fernández, I, van Straaten, HL, van Wezel-Meijler, G, Steggerda, SJ, Dudink, J, Išgum, I, Whitelaw, A, Benders, MJ, Vries, LSd, Han, K, Woerdeman, P, Horst, HJt, Dijkman, KP, Ley, D, Fellman, V, Haan, TRd, Brouwer, AJ, Verlaat, Ev&#x, Go;vaert, P, Smit, BJ, Quijano, TA, Barcik, U, Mathur, A & Graca, AM, 2019, ‘Assessment of Brain Injury and Brain Volumes after Posthemorrhagic Ventricular Dilatation: A Nested Substudy of the Randomized Controlled ELVIS Trial’. Journal of Pediatrics, vol 208., pp. 191-197.e2
• De Vries, LS, Groenendaal, F, Liem, KD, Heep, A, Brouwer, AJ, Verlaat, EV', Benavente-Fernández, I, Van Straaten, HL, Van Wezel-Meijler, G, Smit, BJ, Govaert, P, Woerdeman, PA & Whitelaw, A, 2019, ‘Treatment thresholds for intervention in posthaemorrhagic ventricular dilation: A randomised controlled trial’. Archives of Disease in Childhood: Fetal and Neonatal Edition, vol 104., pp. F70-F75

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View complete publications list in the University of Bristol publications system