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Professor Andrew Newby

Professor Andrew Newby

Professor Andrew Newby
M.A.(Cantab.), Ph.D.(Wales)

Emeritus Professor

Area of research

Vascular Cell Biology

Office Room 147
Level 7,
Bristol Royal Infirmary, Upper Maudlin Street BS2 8HW
(See a map)

Tel. +44 (0) 117 34 23583

Research summary

  • Vulnerable atherosclerotic plaques

Approximately a quarter of a million patients suffer a myocardial infarction (MI) in the UK each year around 120,000 die. MI is caused by thrombosis superimposed on a ruptured or surface-eroded coronary atherosclerotic plaque. Identifying the causes and devising new treatments for these ‘vulnerable’ plaques are therefore internationally recognised priorities. There is also a worldwide effort to improve diagnostic and imaging methods to identify vulnerable patients and localise vulnerable plaques, respectively. Innovations at the BHI place us at the forefront of this effort and our work is well integrated into wider initiatives such as the European ...

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Biography

Andrew Newby is British Heart Foundation Professor of Vascular Cell Biology at the University of Bristol.

Born of English and Polish parents, he graduated in Biochemistry from Cambridge. Following PhD studies in Cardiff and postdoctoral work with Nobel Laureate Martin Rodbell at the National Institutes of Health in Bethesda, USA, his first independent work elucidated the metabolic pathways responsible for production of the cardioprotective metabolite, adenosine.  He later contributed to the identification of the endothelium-derived relaxing factor as nitric oxide.

He is most known, however, for discovering a role for matrix degrading metalloproteinases in vascular smooth muscle cell migration and ...

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Recent publications

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View complete publications list in the University of Bristol publications system

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