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Dr Kara Ranaghan

Dr Kara Ranaghan

Dr Kara Ranaghan

Visiting Senior Research Associate

Office W230
School of Chemistry,
Cantock's Close, Clifton BS8 1TS
(See a map)

Tel. +44 (0) 117 954 6391

Research summary

I became interested in studying enzyme mechanisms as an undergraduate project student and have now spent several years using computational techniques to explore aspects of enzyme reaction mechanisms and catalysis, focusing on the enzymes chorismate mutase, aromatic amine dehydrogenase, and methylamine dehydrogenase. How these enzymes achieve catalysis is at the centre of much lively debate: such as the role of tunnelling in enzyme reactions.

My current project involves studying the reaction mechanism of phosphite oxidation in phosphite dehydrogenase (PTDH).

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Biography

I was awarded an MSci in Chemistry with study in continental Europe by the University of Bristol in 2002 and went on to obtain a PhD in Chemistry in 2006 (also from the University of Bristol).

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Recent publications

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