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Publication - Professor Duncan Wass

    Zirconium-Catalyzed Imine Hydrogenation via a Frustrated Lewis Pair Mechanism

    Citation

    Flynn, SR, Metters, OJ, Manners, I & Wass, DF, 2016, ‘Zirconium-Catalyzed Imine Hydrogenation via a Frustrated Lewis Pair Mechanism’. Organometallics, vol 35., pp. 847-850

    Abstract

    Zirconium-based frustrated Lewis pairs (FLPs) are active imine hydrogenation catalysts under mild conditions. Complexes of the type [CpR 2ZrOMes][B(C6F5)4] utilize the imine substrate itself as the Lewis base component of the FLP. Catalyst performance is a function of ligand structure; in general more bulky, more electron rich cyclopentadienyl derivatives give the best results. However, Cp∗ derivatives are not catalytically active, being stable after initial heterolytic cleavage of H2; this allows experimental verification of the competence of the zirconocene-imine pair in FLP-type heterolytic H2 cleavage. Enamines and protected nitriles are also hydrogenated if an additional internal phosphine base is used.

    Full details in the University publications repository