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Professor Dek Woolfson

Professor Dek Woolfson

Professor Dek Woolfson
BA(Oxon), PhD(Cantab)

Professor of Chemistry and Biochemistry

Area of research

Protein design and its application in bionanotechnology and synthetic biology

Office Chem N410 Mons, Tue-Fri p.m. & Life Sciences 303 Tue-Fri a.m.
Cantock's Close,
Clifton, Bristol BS8 1TS
(See a map)

Alt. +44 (0) 117 39 41314
Tel. +44 (0) 117 954 6347

Research summary

The primary basic research interests of the group are: (A) the informational aspect of the protein-folding problem; that is, how does the sequence of a protein determine its active, three-dimensional structure or fold?  And (B), how can we use this information to design completely new proteins from scratch?  In addition, we design proteins for applications in synthetic biology and medicine.

We tackle these problems using the following multi-disciplinary approach:

  1. We use bioinformatics to garner sequence-to-structure relationships from protein sequence and structural databases.

  2. We test the relationships ("rules for protein folding") that we find in two ways: (a) through ab initio ...

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Selected publications

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