Research in my laboratory aims at finding new therapeutic options for patients with peripheral and cardiac ischaemia. Our efforts are organised in 2 synergic themes: 1) discovering and developing new regenerative approaches (with special emphasis on embryonic stem cells-derived vascular progenitor cells and on NGF gene therapy); and 2) better understanding of molecular mechanisms causing vascular sufferance, especially in diabetes (special focus here is on microRNAs, epigenetics and the p75NTR receptor of neurotrophins).
Our research approach spans from molecular expressional studies, cell biology, in vivo ischaemia and diabetes models and work on clinical samples, with the final objective of translating ...
POSITION TITLES: Full Professor and Chair of Vascular pathology and Regeneration; British Heart Foundation (BHF) Senior research Fellow; Deputy Head of Research in the School of Clinical Sciences
EDUCATION/TRAINING University of Florence, Italy BSc in Biological Science (1987-92) University of California San Francisco, CA, USA travel fellowship (1995) University of Catania (awarding institution for a multicentric PhD program including Florence and Cagliari Universities), Italy PhD in Neurovegetative Medicine/Pharmacology (1996-1999) IDI-Rome, Italy (postdoc) (1998-1999)
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