Directory of Experts
Details for Professor Paul Verkade
| Personal details | |||||
| Name | Professor Paul Verkade | ||||
| Job title | Professor of Bioimaging Professor of Bioimaging |
||||
| Department | Life Sciences Faculty Office University of Bristol School of Biochemistry University of Bristol |
||||
| Personal web page | http://www.bristol.ac.uk/biochemistry/research/pv.html | ||||
| Contact details | This expert can be contacted via the University of Bristol Public Relations
Office. To help us deal with your request, please mention the Directory of Experts when contacting the Public Relations Office. work+44 (0)117 331 8092 email: public-relations@bristol.ac.uk |
||||
| Qualifications | M.Sc., Ph.D.(Utrecht) | ||||
| Professional details | |||||
| Membership of professional bodies | Royal Microscopical Society Chair of the Cryo Microscopy Group |
||||
| Keywords | electron microscopy bioimaging cell biology cell imaging Intracellular trafficking microscopy |
||||
| Areas of expertise | Our research focuses on understanding and visualising intracellular transport processes, both biosynthetic as well as endocytic. Cells have to make new proteins and transport these to the correct places for proper functioning of the cell. Likewise they have to do this for signals (proteins) from the outside environment. Cells have to interpret these signals and then route them correctly. We mainly do this by combining light microscopy with electron microscopy. In these so-called Correlative Light Electron Microscopy experiments we make use of the advantages of doing live cell imaging at the light microscopy level and using the high spatial resolution of the electron microscope (Brown et al., 2009). In this way we can capture specific segregation and fusion events taking place inside the cell (Verkade, 2008). The major project that is currently ongoing is to study the segregation of recycling and degradative cargo in the endocytic pathway. |
||||
| Languages (other than English) |
|
||||