Directory of Experts
Details for Professor Patrick Kehoe
| Personal details | |
| Name | Professor Patrick Kehoe |
| Job title | Gestetner Professor of Translational Dementia Research |
| Department | Bristol Medical School (THS) University of Bristol |
| Personal web page | http://www.bris.ac.uk/clinicalsciencenorth/dementia/staffprofiles/pat |
| Contact details | This expert can be contacted via the University of Bristol Public Relations
Office. To help us deal with your request, please mention the Directory of Experts when contacting the Public Relations Office. work+44 (0)117 331 8092 email: public-relations@bristol.ac.uk |
| Qualifications | B.Sc.(Dub.), Ph.D.(Wales) |
| Professional details | |
| Membership of professional bodies | Executive Member of European Alzheimer's Disease Consortium Scientific Advisory Board Member of Alzgene |
| Keywords | Alzheimer's disease genes blood pressure and dementia hypertension and dementia cognitive decline degrading enzymes angiotensin |
| Areas of expertise | 15 years of working in dementia. Discovered that angiotensin converting enzyme gene (ACE) variation was a risk factor for Alzheimer’s disease (AD) which has prompted a number of investigations by us and others showing that angiotensins are involved in AD. Worked on one of the largest ever genetic linkage studies conducted in AD patients. Have championed that given certain laboratory based findings there may be sufficient data to prompt further work needing to be done and stronger consideration to be made on the potential adverse consequences of prescribing certain types of anti-hypertensive medications to people given possible adverse risks for dementia. Was a lead member of recent efforts to achieve an international consensus for the post-mortem assessment of cerebral amyloid angiopathy. Expertise now refined to roles of genes and protein activity on development, pathology and progression of AD. |
| Media experience | Pre-record pieces to camera for BBC Points West and ITV West as well as for charity-funded fundraising film on Alzheimer's disease. Pre-record and live radio interviews for GWR, Star FM, BBC Bristol and BBC radio 4. |