Directory of Experts
Details for Professor Stuart Siddell
| Personal details | |
| Name | Professor Stuart Siddell |
| Job title | Emeritus Professor |
| Department | School of Cellular and Molecular Medicine University of Bristol |
| Contact details | This expert can be contacted via the University of Bristol Public Relations
Office. To help us deal with your request, please mention the Directory of Experts when contacting the Public Relations Office. work+44 (0)117 331 8092 email: public-relations@bristol.ac.uk |
| Qualifications | B.Sc.(Liv.), Ph.D.(Warw.), Dr. rer. nat. habil. |
| Professional details | |
| Membership of professional bodies | Society for General Microbiology (SGM) American Society of Microbiology (ASM) American Society for Virology (ASV) Gesellschaft für Virologie (GfV) Gesellschaft für Biochemie und Molekularbiologie (GBM) |
| Keywords | molecular biology genetics & pathogenesis of coronaviruses diagnosis of feline coronavirus diseases development of coronavirus antivirals & vaccines |
| Areas of expertise | My research focuses on the structure and function of the coronavirus replication machinery with the goal of identifying novel targets for the development of anti-coronaviral drugs. I have also established and apply coronavirus reverse genetics to the development of novel, live, attenuated coronavirus vaccines. Currently, I am particularly interested in coronavirus proteins that modulate the innate immune response (especially the type 1 interferon response), the adaptation of these proteins during transmission across species, and the manipulation of these proteins to produce coronavirus vaccines. My research includes the study of human coronaviruses, in particular the SARS-coronavirus (SARSCoV), and animal coronaviruses of veterinary importance, for example, Feline infectious peritonitis virus (FIPV). I also study the genetics and pathogenesis of Murine hepatitis virus (MHV), which shares many similarities with SARSCoV. |