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2. Specialised Texts: | ![]() |
These were used to provide some of the most specialised facts
and figures (and diagrams) which I used in order to illustrate
the structure-function relations & characteristic properties
of the different sorts of ion channels. You may feel that the
general texts are sufficient, but should you feel that you need
to think some more about ion channels, then these would be good
place to start. They assume some familiarity with biological
terms and the sort of physics that lies somewhere between 'O'
& 'A'-level. That said, if you have a problem with bioelectricity
etc. these would be worth a look. Hille. Ionic channels of excitable membranes. 2nd Ed. (1992).
I used bits of Chapter 6 'Ligand-gated channels of fast chemical
synapses' but I would recommend Chapter 7 'Modulation,
slow synaptic action, and second messengers', also. Chapter
7 deals very well with the way in which the G protein coupled
receptors (7 membrane spanning -remember?) influence ion channel
function and affect changes in excitability e.g. long term
potential - in relation to learning and memory. Aidley. The physiology of excitable cells 3rd Ed (1989).
Chapters 8 'The nicotinic acetylcholine receptor', 12 'The
contractile mechanism of muscle', 13 'The activation of
muscular contraction' & 14 'The comparative physiology
of muscle' This is a very detailed book with lots of illustrations
from the original research papers included. I find it helps me
to understand and retain information about a system if I am able
to see what experiments have been done - if you find this sort
of mechanistic detail counterproductive, then Aidley is probably
only useful for the pretty pictures. |
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Copyright © 1998 University of Bristol. All rights reserved.
Author: Phil Langton |
Last modified: 20 Nov 2000 09:17 Authored in CALnet |