CNS nicotinic receptors
group I metabotropic glutamate receptors
Areas of expertise
Our group is interested in the neurophysiological changes associated with neurological disease, in particular Alzheimer’s disease and epilepsy. Experimentally the major part of our work involves a host of electrophysiological methods stretching from single channel recording, through cellular neurophysiology in vitro, to tetrode recordings of neuronal activity in vivo. We also utilise a number of optical methods including single cell imaging and photo-activated ion channels such as Channelrhodopsins.
From a receptor point of view our main current interests include estrogen-receptor signalling, CNS nicotinic receptors and group I metabotropic glutamate receptors.