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Details for Professor David Jane

Personal details
Name Professor David Jane
Job title Professor in Chemical Pharmacology
Department School of Physiology, Pharmacology & Neuroscience University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
email:
Qualifications BA(Cantab), PhD(Salf), MRSC
Professional details
Membership of professional bodies Royal Society of Chemistry
American Chemical Society
British Pharmacological Society
Keywords drug design
synthetic organic chemistry
amino acids
medicinal chemistry
computer-aided molecular modelling
neuropharmacology of glutamate receptors
Areas of expertise The group is concerned with the design, synthesis and pharmacological characterisation of analogues of the neurotransmitter glutamic acid in order to obtain selective agonists and antagonists for glutamate receptor subtypes. As glutamate is the major excitatory transmitter in the central nervous system novel pharmacological tools identified in the group can be used to identify the physiological roles of glutamate receptors.