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Unit information: Health sciences: Biochemistry in 2013/14

Please note: you are viewing unit and programme information for a past academic year. Please see the current academic year for up to date information.

Unit name Health sciences: Biochemistry
Unit code ORDS10008
Credit points 30
Level of study C/4
Teaching block(s) Academic Year (weeks 1 - 52)
Unit director Professor. Kelly Moule
Open unit status Not open
Pre-requisites

None

Co-requisites

None

School/department Bristol Dental School
Faculty Faculty of Health Sciences

Description including Unit Aims

Year 1 of programme.

Element 1: Proteins: Structure and function

Element 2: Nucleic acids and genetics

Element 3: Cellular Metabolism

Element 4: Cells and cell regulation

General aims of the Unit:

  1. To provide an introduction to biochemistry and to emphasise its relevance to the subject of dentistry.
  2. To provide a foundation that will enable students to understand biochemical techniques and their relevance to clinical science.
  3. To provide a foundation upon which other pre-clinical and clinical units will build later in the programme.
  4. To demonstrate how biochemistry has advanced the study of both normal and diseased states.
  5. To demonstrate that biochemistry is concerned with the chemical basis of normal biological structure and function and is essential for the understanding of living processes in health and disease.
  6. To show that fundamental events in biology involve molecular change and provide the dental undergraduate with a scientific foundation for dentistry as well as an awareness of how science advances biomedical knowledge.
  7. To provide practical experience in laboratory techniques and training in the interpretation of results, calculation and the use of scientific units.

Intended Learning Outcomes

Students should obtain a knowledge and understanding of the following:

  1. The structure and function of macromolecules within the cell and in the extracellular environment.
  2. The basic concepts in nutrition and cellular metabolism, including details of important pathways.
  3. The co-ordinate regulation of biochemical pathways and the mechanism of hormone action.
  4. The role of nucleic acids in directing protein synthesis an understanding of the acquisition of new genetic information by mutation and viral transformations
  5. Molecular genetics and molecular biology techniques.
  6. The fundamentals of medical biochemistry.
  7. The basic biochemistry of the oral cavity and its relevance to dentistry.
  8. Basic biochemical techniques and their use in disease diagnosis.

A student should acquire the skills necessary to:

  1. Perform basic numerical manipulations and scientific calculations.
  2. Carry out practical work using standard laboratory apparatus and demonstrate the proper use of scientific units.
  3. Relate the biochemistry they have learnt to the practice of dentistry.

Teaching Information

Lectures, workshops, laboratory sessions.

Assessment Information

Formative assessments:

  • Essay writing, data handling and calculation questions performed during workshops.

Summative assessments:

  • Laboratory pre and post lab tests and write ups – contribute 5% of end of year mark.
  • Midsessional paper (1.5 hr) contributes 15% of end of year mark.
  • End of year paper (3 hr) contributes 80% of end of year mark.
  • Midsessional and end of year examination papers comprise MCQs, essays, data handling and interpretation questions.

Reading and References

  • Baynes & Dominiczak. 3rd Edition (2009) Medical Biochemistry. Mosby.
  • Devlin TM. 7th Edition. (2009) Textbook of biochemistry with clinical correlations. Wiley and Sons.
  • eBiolabs

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