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Unit information: Immunopathology and Applied Immunology in 2015/16

Please note: you are viewing unit and programme information for a past academic year. Please see the current academic year for up to date information.

Unit name Immunopathology and Applied Immunology
Unit code PANM33002
Credit points 20
Level of study H/6
Teaching block(s) Teaching Block 4 (weeks 1-24)
Unit director Professor. Wuelfing
Open unit status Not open
Pre-requisites

PANM22041 Infection and Immunity

PANM22042 Cellular & Molecular Pathology

MOLG22100 Recombinant DNA Technology

MOLG22200 Gene Expression and Rearrangement

FMVS20001 Biomedical Research, Employability and Enterprise Skills

Co-requisites

3 from level 6/H lecture units and Research Skills unit.

School/department School of Cellular and Molecular Medicine
Faculty Faculty of Life Sciences

Description

Immune responses can have harmful direct effects and side effects. Selected examples of such pathological effects are covered including various autoimmune diseases, the immunopathology of helminth diseases, allergy and the pathogenesis of asthma. Immunodeficiencies are also considered. Vaccination has been a success story for immunology, but there are many diseases, both microbial and conditions such as cancer and autoimmune diseases, where vaccines remain to be developed. Here the problems of evading the immune response and designing effective vaccines are covered. The problems of transplant rejection and how they might be overcome are also included. The topics discussed in this section include: Trends in paediatric vaccinology, Current problems in viral vaccination, Bone marrow transplantation and immune reconstitution, Graft versus host disease, Immunity to tumours and Cell based cancer vaccines for leukaemia and solid tumours. Lectures in weeks 5-8.

Aims:

This topic has two aims. It provides a comprehensive coverage of diseases, which develop as a consequence of inappropriate immune responses and as a result of deficiencies in the immune system. Secondly, it provides an introduction to disease processes and how this knowledge is used to manipulate the immune system through vaccination and other immunotherapies to fight infection, allergy, autoimmunity and tumour development.

Intended learning outcomes

Knowledge and Understanding of current topics in immunology and how knowledge of immunology can be applied therapeutically. Familiarity with the scientific literature pertaining to the topic and an ability to evaluate this literature critically.

Teaching details

Lectures, Data Handling Session, Journal Review Session.

Independent Study: Students are expected to study the recommended literature.

Assessment Details

Summative 3 hour written exam, to include 3 essays chosen from 6.

Reading and References

Reviews and primary articles from the current scientific literature.

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