Unit information: Cellular and Molecular Pathology in 2015/16

Unit name	Cellular and Molecular Pathology
Unit code	PANM22042
Credit points	20
Level of study	I/5
Teaching block(s)	Teaching Block 2 (weeks 13 - 24)
Unit director	Dr. Brown
Open unit status	Not open
Pre-requisites	None
Co-requisites	None
School/department	School of Cellular and Molecular Medicine
Faculty	Faculty of Life Sciences

Description including Unit Aims

The cellular and molecular basis of the most important types of disease that are not directly related to infectious microorganisms.

Intended Learning Outcomes

At the end of the unit a successful student will be able to:

1. describe examples of human genetic diseases,
2. discuss genetic testing,
3. explain the causes, mechanisms and prevention of cancer,
4. discuss transplantation and HLA,
5. list and explain the types of hypersensitivity reaction,
6. discuss examples of autoimmune disease and HLA associated diseases,
7. carry out and describe molecular and cytogentic experimental techniques,
8. interpret data and solve problems,
9. present scientific information and complex arguments in written and oral form,
10. undertake the further study of genetics, cancer and immunopathology at Level 6.

Teaching Information

Lectures

Tutorials

Practicals

Assessment Information

Summative assessment:

Oral presentation (5%)

eBiolabs pre-lab quizzes and post-lab assignments, and laboratory write-ups (5%)

1-hour essay under exam conditions (5%)

1-hour mid-unit assessment including multiple choice questions (10%)

2.5-hour written exam (summer) including multiple choice questions and two essays (75%)

The exams will cover learning outcomes 1-9.

The laboratory write-ups will assess learning outcomes 7-9.

The essay and oral presentation will cover learning outcome 9 and any from 1-6.

Formative assessment:

For formative purposes students will receive feedback as follows:

• The essay will be marked and returned with written feedback.

• Electronic feedback will be provided for the pre-lab and post-lab work via eBiolabs.

• Laboratory write-ups will be marked and returned.

• Oral presentations will be marked and subject to verbal feedback during the tutorial and a written feedback sheet provided.

• Feedback during practical classes will be provided by staff and demonstrators.

• Unit assessment marks will be provided and additional feedback will be provided in a session with the Unit Director.

• A breakdown of marks for the summer exams will be provided and additional feedback will be provided by the Unit Director on request.

Reading and References

The Biology of Cancer. Robert A Weinberg, 2007. (GS Garland Science)

Introduction to the Cellular and Molecular Biology of Cancer. 4th edition. Eds. M.A. Knowles & P.J. Selby, 2005. (Oxford University Press)

Human Molecular Genetics. 3rd edition. P. Sudbery & I Sudbery, 2009. (Pearson/Prentice Hall)

Emery’s Elements of Medical Genetics. 14th edition. P. Turnpenny & S. Ellard, 2011. Churchill Livingstone Elsevier

Janeway’s Immunobiology 8th edition, by Kenneth Murphy, 2011. (Garland Science)

All textbooks are available in the Medical Sciences library.