Unit information: Core Special Chemistry for Life Scientists in 2014/15

Unit name	Core Special Chemistry for Life Scientists
Unit code	CHEMM0010
Credit points	20
Level of study	M/7
Teaching block(s)	Teaching Block 4 (weeks 1-24)
Unit director	Professor. Wyatt
Open unit status	Not open
Pre-requisites	CHEM30006, CHEM30011, CHEM30014,CHEM30015
Co-requisites	None
School/department	School of Chemistry
Faculty	Faculty of Science

Description including Unit Aims

This unit develops the organic and inorganic chemistry given in CHEM 30870, 30875 & 30880 to build to an advanced stage for the MSci level of study. The unit covers areas of the subject that are considered core not just to organic and inorganic chemists, but of interest and utility to those specialising in physical and theoretical chemistry. The organic topics covered are supramolecular chemistry and the investigation of organic reaction mechanisms. The inorganic topics covered are the chemistry and applications of second- and third-row transition metals and medicinal applications of metals. Workshops are integral to the unit.

This unit aims to provide a high level of understanding of the physical organic aspects of supramolecular and mechanistic chemistry, and transition metal chemistry at a level appropriate for an MSci student. The unit will contain concepts and material that is appropriate for application in other areas of chemistry and potentially of utility in the research project.

Intended Learning Outcomes

• • Understanding of how covalent interactions are key for Supramolecular
  • Understanding of how these interactions allow selective binding of ions
  • Understanding of enantioselective supramolecular interactions occur
  • An appreciation of the importance and philosophy of investigation of reaction mechanisms
  • An ability to conduct simple analysis of the kinetics of reactions in relation to mechansim
  • An ability to design isotopic labelling experiments
  • An appreciation of the origins and utility of linear free-energy relationships
  • Appraise the differences between the 1st and 2nd/3rd row transition metals
  • Understand the role of metals in diagnosis and therapy

Teaching Information

Lectures, workshops (classes of 20 students with two staff members) and masterclasses (interactive seminar sessions of the whole class) and independent study. The Dynamic Laboratory Manual provides important e-learning resource in advance of workshop sessions. Pre-workshop online material will be provided to assist students with the contact workshop.

Assessment Information

Students will be assessed by written examination totalling 90 minutes (summative 100%).

Reading and References

Organic Chemistry, J. Clayden, N. Greeves, S Warren and P Wothers, Oxford, 2001 (currently 29 copies in the library) Modern Physical Organic Chemistry, E. V. Ansyln, D. A. Dougherty, University Science Books, California, 2006 (currently 3 in library; plus a copy of the 'solutions manual' to the problems) Supramolecular Chemistry, P. D. Beer, P. A. Gale. D. K. Smith, Oxford Chemistry Primer, 1999 (currently 2 in library) Supramolecular Chemistry, J. W. Steed, J. L. Atwood, Wiley 2009 (currently 2 in library) Shriver and Atkins' Inorganic Chemistry, P. Atkins, T. Overton, J. Rourke, M. Weller, F. Armstrong, 5th Edition, 2010