The Sunflower study is a UK-wide RCT looking to determine whether testing for common bile duct (CBD) stones before gallbladder surgery is effective or not in patients at low or moderate risk of CBD stones. This is an informative study animation for participating clinicians and healthcare professionals.

Definition of an invasive procedure: There is currently no widely accepted definition of an invasive procedure and the terms ‘surgery’ and ‘interventional procedure’ are characterised inconsistently. Our animation describes work we have done to propose a comprehensive definition for invasive procedures which addresses the limitations of those currently available.

Optimising blinding or masking of participants in a surgical trial: Blinding of study participants and personnel involved in a surgical RCT is often perceived to be challenging. Our informative video showcases a real-life example of how it is possible to blind study participants in a multicentre RCT of minimally invasive or open surgery for oesophageal cancer. 

Core Outcome Set for Burns Care Research (COSB): Decision-making for burns care can be challenging. Watch our animation to discover how an agreed set of the most important outcomes to measure and report in randomised controlled trials in burn care will facilitate effective evidence synthesis to support clinical decision-making.


Definition of an invasive procedure

What is an invasive procedure? A definition to inform study design, evidence synthesis and research tracking.

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Optimising blinding or masking of participants in a surgical trial.

The feasibility of a randomized controlled trial of esophagectomy for esophageal cancer - the ROMIO (Randomized Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial.

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Comparing open and minimally invasive surgical procedures for oesphagectomy in the treatment of cancer: the ROMIO (Randomized Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial.

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Core Outcome Set Burns Research (COSB)

Agreement on what to measure in randomised controlled trials in burn care: study protocol for the development of a core outcome set.

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A short 'how to' animation describing study design, managment and engaging surgical trainees in trials. Created by 'Jammond Makes'. 

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