Public Lecture by Professor Stuart Mundell
Wills Memorial Building, Queens Road, Bristol, BS8 1RJ
Heart attacks occur when a blockage called a thrombosis develops in the blood vessels of the heart. Platelets, the major blood cell involved in thrombosis development, can be switched on to become sticky by a wide variety of mediators. These tiny blood cells normally help your body form clots to stop bleeding. If one of your blood vessels gets damaged, it sends out signals that are picked up by platelets. The platelets then rush to the site of damage and form a plug, or clot, to repair the damage. However, when platelets activate too much or at the wrong time and place the result is thrombosis, leading to heart attacks and stroke.
Research from the Bristol Platelet Group continues to develop our understanding of the complex nature of platelet function. In this public lecture Professor Stuart Mundell from the Bristol Platelet Group will outline how their translational research ranging from patients who suffer with mild bleeding to those on current antiplatelet therapies continues to help in the development of new, safer and more effective drugs for the treatment and prevention of cardiac disease.