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Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC

12 January 2018

Research by led by John Crosby, Matt Crump with collaborators at University of Irvine, USA has recently been featured in a paper in Chemical Biology

DpsC crystal structures described in this paper reveal the architecture of the active site and the mechanisms of selection and transfer of the novel starter unit for daunorubicin, a polyketide with anticancer activity.

Further information

Paper: Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC

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