Flux-sensing by kinase/ Transporter pairs-need-based activation of antibiotic resistance
Dr Susanne Gebhard, University of Bath
Lecture theatre C44, Biomedical Sciences Building
Bacteria are found in almost any habitat on Earth, and one key to their success is their extraordinary ability to monitor their environment and respond to changes and stresses they might encounter. They achieve this by means of sophisticated signalling pathways that can relay specific information from the outside to the inside of the cell and trigger the most appropriate response. Susanne's group is interested in understanding how these signalling systems work, what information they gather, how the different protein components communicate, which genes are switched on or off as a result of signalling, and how these responses adapt the bacterium to the encountered stress.
Host: Dr Ruth Massey