Inaugural Lecture by Professor Rafael E Carazo Salas
Professor Rafael Carazo Salas
Old Council Chamber, Wills Memorial Building
Speaker: Professor Rafael E Carazo Salas
Title: From observing to predicting to controlling how cells function
Date: 13 March 2018
Time:17:00 (followed by drinks reception at 18:00)
Venue: Old Council Chamber, Wills Memorial Building
Admission: Free, but requires booking in advance via Eventbrite
The Personalized, Precision Medicine of the future will rely on being able to access highly refined information about our cells and our genome, and leveraging that information to predict accurately how our cells & tissues can be fixed or replenished at will.
In this lecture, I will describe how large-scale microscopic imaging technologies and predictive data analysis approaches can together play a crucial role toward that vision.
I will illustrate this by giving examples of how my group has combined those approaches in the past decade to obtain complete catalogues of genes and proteins controlling basic biological processes within cells, and achieve a better understanding of how genes and proteins collectively give rise to integrated cell functions.
I will then explain how we are pioneering similar technologies to obtain quantitative, predictive knowledge of how human stem cells can be differentiated into target tissue types, with the longer-term view to applying those technologies to precisely engineer tissues in vitro for therapeutics applications.