UK universities will work together to improve research quality and reproducibility10 December 2019UK universities will collaborate to improve the quality of UK academic research output. Whilst the UK is at the leading edge of research globally, there is a need to constantly strive to improve in order to retain that positions. Crucially, institutions must produce research that is rigorous, robust and of high-quality, to ensure that the UK retains its reputation for producing world-leading research.
Being active reduces risk of prostate cancer5 December 2019Prostate cancer is the most common cancer in men in the UK*, yet we still don't know all of its causes. The largest ever study to use genetics as a measurement for physical activity to look at its effect on prostate cancer, reveals that being more active reduces the risk of prostate cancer. Over 140,000 men were included in the study, of which, 80,000 had prostate cancer.
£18.5 million boost for South West biosciences24 October 2019PhD training across the biosciences has received a massive boost thanks to a £18.5 million funding award from the Biotechnology and Biological Sciences Research Council (BBSRC, part of UK Research and Innovation) to the University of Bristol-led South West Biosciences Doctoral Training Partnership (SWBio DTP).
Scientists join forces to shed new light on ageing and wound healing11 October 2019Researchers from the Universities of Manchester and Bristol have been granted £4 million to investigate how cells govern the processes of ageing and wound healing and how this is influenced by the circadian (day/night) cycle. Their findings could help to improve wound healing and identify strategies to treat diseases like osteoarthritis.
Adult fly intestine could help understand intestinal regeneration25 September 2019Intestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research by the universities of Bristol, Heidelberg and the German Cancer Research Center (DKFZ) have found that Nox-ROS-ASK1-MKK3-p38 signaling in IECs integrates various stresses to facilitate intestinal regeneration.
Risk of bias in evidence underpinning approval of new cancer drugs raises questions23 September 2019Around half of trials that supported new cancer drug approvals in Europe between 2014 and 2016 were judged to be at high risk of bias, a study published by the British Medical Journal (BMJ) has found. The research was led by the London School of Economics, with methodological input from the National Institute for Health Research (NIHR) Bristol Biomedical Research Centre (BRC) and NIHR Collaboration for Leadership in Applied Health Research and Care West (CLAHRC West).
Identifying risks and improving pregnancy care in childhood cancer survivors17 September 2019Thanks to improved survival and assisted fertility technologies like IVF, more women who had cancer treatment as a child or young adult are now able to have children. Unfortunately, evidence suggests that they are more likely to experience problems during pregnancy, including an increased risk of their babies being born prematurely. Dr Melanie Griffin of University Hospitals Bristol NHS Foundation Trust is looking at the long-term impact of cancer treatment involving bone marrow transplantation on women’s reproductive health. She hopes to identify new ways to improve care for these childhood cancer survivors before and during their pregnancy, reducing the chances of their babies being born too soon.
Bristol immersive VR documentary to be shown at Venice Film Festival13 September 2019From Bristol to the big screens of Venice Film Festival, Virtual Reality film The Waiting Room, [commissioned by the Virtual Realities – Immersive Documentary Encounters research project] will be premiered at the annual event which starts today [28 August to 7 September] to a star-studded audience of cinema enthusiasts.
MRI assisted biopsies more effective at detecting prostate cancers3 September 2019Using MRI scans to target biopsies is more effective at detecting prostate cancers that are likely to need treatment than standard ultrasound guided biopsies alone, according to research published in JAMA Network Open. The research, led by the National Institute for Health Research (NIHR) and Universities of Bristol, Ottawa, Exeter and Oxford, combined the results from seven studies covering 2,582 patients.
Mendelian randomisation cancer and nutrition workshop1 August 2019The Mendelian randomisation cancer and nutrition workshop, hosted by the Integrative Cancer Epidemiology Programme (ICEP) in Bristol on 15 and 16 July, attracted 20 experts to assess and discuss the question: What are the challenges in nutritional cancer epidemiology and how can Mendelian randomization address them?
James Yarmolinsky wins CRUK fellowship30 July 2019Integrative Cancer Epidemiology Programme (ICEP) researcher James Yarmolinsky has been awarded a CRUK 3-year fellowship, starting in October. The research will focus on "Evaluating the role of inflammation in cancer: robust target identification using genomic data."
Making the immune system better at recognising cancer23 July 2019A team at University of Bristol, led by Professor Linda Wooldridge, is engineering a type of immune cell that might be able to better target cancer cells. This could potentially lead to new therapies which could help the immune system combat cancer with fewer difficult interventions.
Understanding how cancer cells eat16 July 2019Meet Dr Emma Vincent as she tells us about her research and the artwork inspired by her work that reflects on the pathways that we and our cells can make
£9 million boost for health research in the west country12 July 2019Health researchers in the west country have been given a £9 million award from the Government's Department of Health and Social Care (DHSC) to enable them to tackle the area's most pressing health problems. The funding will enable new research projects including forecasting demand in hospitals, increasing people's physical activity levels, supporting people who self-harm and improving outcomes for children in care.
Understanding the unintended consequences of healthcare apps9 July 2019Dr Andrew Turner, Senior Research Associate, CLAHRC West, discusses the move towards ‘digital first’ care, the possible unintended consequences of healthcare apps, and how the DECODE study aims to improve the adoption of a range of digital health tools in primary care by understanding these unintended consequences.
Cancer Research UK’s obesity campaign5 July 2019Cancer Research UK (CR UK) states that their latest obesity campaign aims to stimulate a government policy response to ‘junk food’ advertising to children. Focusing on policy change rather than individual behaviour change is a laudable aim. However, the charity’s approach has been challenged by the public, researchers, and healthcare professionals.
GPs should not use inflammatory marker tests to rule out serious conditions18 June 2019Blood tests that detect inflammation, known as inflammatory marker tests, are not sensitive enough to rule out serious underlying conditions and GPs should not use them for this purpose, according to researchers from the University of Bristol's Centre for Academic Primary Care, University of Exeter and the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West).
Zebrafish capture a 'window' on the cancer process4 June 2019Cancer-related inflammation impacts significantly on cancer development and progression. New research has observed in zebrafish, for the first time, that inflammatory cells use weak spots or micro-perforations in the extracellular matrix barrier layer to access skin cancer cells.
£6.6 million for major UK non-communicable disease prevention project10 May 2019The University of Bristol, in partnership with the Universities of Bath, West of England, Manchester, Reading and Cardiff and Bristol City Council and Greater Manchester Combined Authority, has been awarded £6.6 million by the UK Prevention Research Partnership (UKPRP) to tackle unhealthy urban planning and development linked to non-communicable diseases (NCDs) such as heart disease, obesity, poor mental health, cancer and diabetes.
Boost to Bristol’s research in Africa29 April 2019A generous £1 million gift from The Perivoli Trust will create new roles and opportunities for Bristol researchers to tackle key challenges and pioneer innovative solutions for the most pressing concerns on the continent.
Welding with stem cells for next-generation surgical glues23 April 2019Scientists at the University of Bristol have invented a new technology that could lead to the development of a new generation of smart surgical glues and dressings for chronic wounds. The new method, pioneered by Dr Adam Perriman and colleagues, involves re-engineering the membranes of stem cells to effectively “weld” the cells together.
Recognition in medicinal chemistry1 April 2019Prof Varinder Aggarwal of the School of Chemistry has been recognised for his work in the
field of synthetic chemistry after being awarded the prestigious Yamada-Koga Prize 2019 from the University of Tokyo.
New Max Planck-Bristol Centre for Minimal Biology launched29 March 2019Building stripped-down versions of life using protocells, genome delivery systems and synthetic cytoskeletons comprise some of the groundbreaking research due to take place at a new Centre launched at the University of Bristol today [Wednesday 27 March]. The Max Planck-Bristol Centre for Minimal Biology, a partnership between the University of Bristol and the Max Planck Society for the Advancement of Science (MPG) in Germany, aims to advance the future of health and medicine by understanding the fundamental nature of life.
UK Research and Innovation Global Research Hubs 14 February 2019Scientists from the University of Bristol will be sharing their expertise as part of two new £20 million UK Research and Innovation Global Research Hubs funded through the Global Challenges Research Fund (GCRF). The first will focus on urban disaster risk and the second aims to tackle the challenge that nitrogen pollution poses for the environment, food security, human health and the economy in South Asia.
2019 Hooke Medal of the British Society of Cell Biology14 February 2019Eugenia Piddini, Professor of Cell Biology and Wellcome Trust Senior Research Fellow, has been awarded the 2019 Hooke Medal in recognition of her outstanding contribution to cell biology and as an emerging leader in this field.