Level III Advanced Organic Practical Course 1998-99
Contents
 
Experiment Special Features  Related Course Points 
Evans Alkylation Use of LDA, enantio- and diastereo-selectivities TCG 4
Enzyme Resolution Enantioselectivity. Enzymes in organic synthesis RJC 2
Horner-Wittig P stabilised carbanion. Stereospecificity, Pure E or Z alkenes CLW 4
Sharpless Asymmetric Dihydroxylation Chiral ligand, catalysis, product value, effect of recrystallisation on ee TCG 3
Structure Elucidation of a commercial pharmaceutical  Real life interest, Using School of Chemistry analytical services(elemental, NMR, MS) --- 1
Aldol Coupling Stereochemistry Use of nOe to determine relative stereochem. Simple protecting group chemistry RJC 2
Nickel Catalysed Coupling Isotope labelling. Catalytic coupling. Sublimation as a purification. GCL-J 3