Monosaccharides and Amino Acids

Year 3 lectures
Dr Russell J. Cox

  Recommended Books :

• Vollhardt and Schore ' Organic Chemistry' 2nd Ed, Chapters 24, 26
  
• Jones 'Amino Acids and Peptide Synthesis' Oxford Chemistry Primer
  
• Collins and Ferrier ' Monosaccharides' - Library
  
• Kirby 'Stereoelectronic Effects' Oxford Chemistry Primer
  
• Greene and Wuts 'Protective Groups in Organic Synthesis' 2nd Ed. - Library

Monosaccharides and amino acids are multifunctional compounds. This course will explore the chemistry of these important classes of natural products by concentrating on individual functionalities. Monosaccharides will be discussed in terms of the chemistry of alcohols (primary and secondary) and carbonyls (ketones and aldehydes) while the chemistry of amines and carboxylic acids will form the basis of understanding amino acids. Structural features (such as the anomeric effect) will also be considered and their bearing on reactivity examined. An important linking theme will be the use of protective groups and their chemo- and regio-selectivities. The use of protective groups during the synthesis of bio-active polysaccharides and polypeptides will be discussed.

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