Winning entries for Art of Science 2015 competition 30 November 2015Wolfson Bioimaging Facility users were yet again successful in this year’s Art of Science competition. Prize-winning images were submitted by Ilona Aylott (confocal), Jenna Cash (multiphoton) and Catherine Twomey (Confocal).
First steps towards new therapy for diseases caused by defective anion transport5 November 2015Research by a team at the University of Bristol has taken the first steps towards new treatments for inherited diseases such as cystic fibrosis; one form of Bartter’s syndrome (severe salt loss from the kidney); and two forms of myotonia (muscle stiffness), which are linked to defective movement of anions, such as chloride, across cell membranes.
Ballooning platelets and the future of anti-thrombotic drugs7 September 2015Membrane ballooning in platelets during the blood-clotting process is driven by a coordinated system of salt and water entry which may be modified pharmacologically, a new study from the University of Bristol has found. The research could ultimately lead to the development of better ‘blood-thinning’ drugs for patients who experience complications with or are resistant to existing antiplatelet drugs such as aspirin.
Watching how signalling regulates T cell activation5 August 2015By combining visualisation of the subcellular distributions of more than 60 signalling intermediates with microscopy across size scales Christoph Wülfing’s group have gained insight into how T cells regulate their activation
Automated live cell imaging with IncuCyte ZOOM 17 July 2015The latest addition to the Wolfson Bioimaging Facility is a dedicated live cell imaging system offering automated image acquisition and analysis with ‘high throughput’ capabilities.
Tissue ‘scaffold’ technology could help rebuild large organs24 June 2015Scientists have developed a new tissue ‘scaffold’ technology that could one day enable the engineering of large organs. Research led by the Universities of Bristol and Liverpool has shown that it is possible to combine cells with a special scaffold to produce living tissue in the laboratory. It is hoped this can then be implanted into patients as a way of replacing diseased parts of the body.
Leica SP8 Digital Light Sheet Workshop: 13th and 14th May 201527 April 2015The University of Bristol’s Wolfson Bioimaging Facility in collaboration with Leica Microsystems is hosting one of the first demonstrations of the DLS light sheet microscope in the UK. This technique allows fluorescence imaging of model organisms, tissues and cell spheroids at high speed and with minimal photodamage.