Insulin-like Growth Factors and Metabolic Endocrinology Group (IMEG)

Our research at the IGFs and Metabolic Endocrinology Group (IMEG) is focused on how nutrition and metabolism contribute to the development of major chronic disorders, with a specific interest in the role of insulin-like growth factors (IGFs).

Insulin-like growth factors (IGFs), together with insulin, are fundamental, nutritionally-dependent regulators of growth and metabolism. Many of the major chronic illnesses that increasingly burden our health services have been linked to a Western diet and lifestyle and are far less prevalent in large regions of the world .

We have been investigating the biology of IGFs and related factors and how they may mediate the effects of nutrition on chronic illness. Our research includes cell biology studies, translational clinical investigations and population epidemiology. We have focused on the major epithelial cancers and on obesity and more recently on interactions between these two conditions.

Research interests

Group Leads

Prof Jeff Holly
Professor of Clinical Sciences
Tel: 0117 41 48045
jeff.holly@bristol.ac.uk

Dr Claire Perks
Reader in Tumour Cell Biology
Tel: 0117 41 47897
claire.m.perks@bristol.ac.uk

Contact

IGF & Metabolic Endocrinology Group
Learning and Research Building
Second Floor
Southmead Hospital
Westbury-on-Trym
Bristol BS10 5NB
United Kingdom
angie.mitchell@bristol.ac.uk
Tel: +44(0)117 41 48051

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