Bristol Randomised Trials Collaboration

The Bristol Randomised Trials Collaboration (BRTC) is an academic clinical trials unit with full UKCRC registration. We are based within the School of Social and Community Medicine in the University of Bristol. The co-directors are Athene Lane and Chris Metcalfe.

We have a particular interest in pragmatic randomised trials that are considered “hard to do” because of complexities in, for example, access to patients, the intervention, or trial design. As part of this focus the BRTC does support those feasibility studies involving publishable methodological sub-studies to which we can contribute, and which are likely to lead to full pragmatic trials the BRTC would be well-placed to support.

Please approach the BRTC at an early stage if you are interested in working with us.

The BRTC will start working with a principal investigator whilst the grant application is being written, and is unable to adopt trials which have already secured funding. The BRTC is also not normally able to support studies with notice of less than eight working weeks before the grant application deadline, since we would be unable to contribute fully without this impacting on our support to other applications aiming for the same deadline. We will still consider approaches made later than this, especially if the funder's deadline for a commissioned call requires a rapid application, but we will not take on additional projects if we are already fully committed.


This unit receives National Institute for Health Research CTU Support Funding. This funding has been awarded to support the unit in developing and supporting NIHR trials.

Working with us

Complete a collaboration application form on the Bristol Research Support Partners site.

Randomisation System

Access our automated Randomisation System


Bristol Randomised Trials Collaboration (BRTC)
School of Social and Community Medicine
University of Bristol
Canynge Hall
39 Whatley Road
Bristol, BS8 2PS
United Kingdom
Tel: +44(0)117 331 3915
Fax: +44(0)117 928 7236