Cortisol effects on locus coeruleus activity (CELCA) - Version 2.0
14 October 2019
This is a research project looking at how manipulating certain stress hormones and neurotransmitters affects a part of the brain called the locus coeruleus.
What does it involve?
- Picking up tablet medication the day before testing and taking this medication yourself at home.
- Providing a urine sample the day before testing to allow for pregnancy and drug testing.
- Attending testing which will involve sitting in front of a computer screen and responding to certain auditory tones as quickly as possible.
- Testing will take about 45 minutes.
- After testing there will be a break of at least 10 days after which you will be asked to repeat the above procedure but with a different tablet medication.
- This will occur 4 times in total with 4 different tablet medications.
- There are minimal side effects associated with these treatments. They are all medications that are commonly prescribed.
- There are no direct benefits however we will reimburse you £100 for your time spent on the whole study period. This is to compensate you for the inconvenience of missing work or university.
- You may also receive up to £80 reward if you perform well in the 4 auditory tasks.
You are eligible if you meet ALL of the following criteria:
- Male or female, aged 18-64
- Not pregnant or breastfeeding
- Fit and healthy with no medical problems
- Not taking steroid or hormonal medications nor illegal substances
- Fluent in English
- No problems with eye sight (can read large text without glasses or with contact lenses)
- No history or diagnosis of immunosuppressive disorders, blood disorders or psychiatric illness.
- BMI in the 19-29 range
If you are interested in taking part or finding out more
Please contact Laura Cole (PhD Student in Neuroscience)