Medicines and Prescribing research
The Medicines and Prescribing research group at the Centre for Academic Primary Care (CAPC) is a small but rapidly expanding multidisciplinary team of researchers. We have broad interests covering a range of topics related to the rational and safe use of medicines in primary care.
Areas of interest include:
- medicines optimisation
We also have active collaborations with researchers at the Universities of Cambridge, Nottingham, Oxford and Dundee, and support the provision of undergraduate teaching on pharmacology and therapeutics at Bristol Medical School.
Medicines and prescribing facts
Medications are the main therapeutic intervention offered by clinicians to improve health, with most prescribing occurring in primary care.
Over 1 billion items are dispensed annually in primary care in England alone, and prescribing accounts for the biggest proportion of non-staff expenditure by the NHS.
Over half of patients in their 70s are on at least four regular medications.
Barbara has a PhD in social and cultural history, and provides administrative support for the group.
Rachel is an experienced epidemiologist and supports broader work in the Department of Population Health Sciences using the CPRD database. She is involved with several pharmacoepidemiological studies, including leading a project investigating the effectiveness of cardiovascular preventative treatment in patients with multimorbidity.
Polly is a GP and NIHR In-Practice Fellow. She has interests in multimorbidity, polypharmacy and deprescribing. She is currently undertaking a qualitative study exploring pharmacist and GP perspectives on medication reviews and collaborative working.
Debbie is a Research Fellow with longstanding and diverse research experience and expertise within a primary health care setting. Her research interests include medicines optimisation and users' experience of medication review.
Rupert is a GP and Clinical Pharmacologist, and Consultant Senior Lecturer. He has particular interests in polypharmacy and electronic health records, and is chief investigator for the IMPPP trial. He co-authored the influential King's Fund report on polypharmacy.
Peter is a researcher with quantitative methodological expertise in using routine and individual patient data with an interest in primary care service use. He is currently supporting a project using CPRD, developing a novel measure of polypharmacy.
- IMPPP: Improving Medicines use in People with Polypharmacy in Primary Care. Payne RA, Salisbury C, Round J, Morris R, Jameson C, Dreischulte T, Guthrie B, Chew-Graham C. Funder: NIHR Health Services and Delivery Research (2018-2022)
- Developing a measure of inappropriate polypharmacy in primary care. Payne RA, Hay A, Morris R, MacLeod J, Avery A, Rodgers S, Burt J, Campbell S. Funder: NIHR School for Primary Care Research (2016-2018)
- Impact of hospital admission upon patterns of primary care prescribing. Payne RA, Purdy S, Morris R. Funder: NIHR School for Primary Care Research (2016-2018)
- The effectiveness of CVD preventative treatment in a multi-morbid population. Denholm R, Macleod J, Payne RA, Morris R, Davies N. Funder: NIHR School for Primary Care Research (2017-2019)
- What is the role of genetics in primary care? Payne R. Funder: NIHR Evidence Synthesis Working Group. Funder: NIHR School for Primary Care Research (2017-2020)
- Patient experiences and perceptions of medication review in general practice. McCahon D, Horwood J, Payne RA, Duncan P. Funder: RCGP SFB (2018-2019)
- Using national administrative data to evaluate new models of primary care prescribing. Payne RA, Denholm R, McCahon D, Kontopantelis E, Rodgers S. Funder: NIHR School of Primary Care Research (2018-2019)