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default for PI page turquoise Dr E. Clea Warburton
Visual recognition and spatial memory

Full contact details
E.C.Warburton@bristol.ac.uk
Department of Anatomy

Projects -  Diseases -  Processes -  Techniques -  Equipment -  Funding -  Collaborations -  Teaching -  Group members -  Publications & further information

Research

Our research focuses upon the brain regions involved in visual recognition and spatial memory, particularly the perirhinal and prefrontal cortices and the hippocampus, and the cellular and molecular mechanisms that may underlie memory processes within these regions.

Anatomy department website
MRC CentreFurther information on the work of the group may be found at the MRC Centre for Synaptic Plasticity website.


Current projects include:
  • Neural regions involved in processing visuo-spatial information
  • Neuronal plasticity underlying recognition in the perirhinal cortex
  • Role of peririhinal and prefrontal cortex in recognition memory

Possible future projects and direction of research:
Developments in integrating the behavioural assessment of learning and memory with advances in pharmacology and molecular biology to further understand the cellular mechanisms underlying learning and memory processes.

Diseases related to this field of research
Amnesia, Alzheimer's Disease

Processes and functions relevant to this work
Learning, memory


Techniques in routine use
Behavioural assessment of learning and memory, immunocytochemistry, fluorescence microscopy


Equipment in routine use
Fluorescence microscope/automated counting software, behavioural testing apparatus

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Projects -  Diseases -  Processes -  Techniques -  Equipment -  Funding -  Collaborations -  Teaching -  Group members -  Publications & further information

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Grants and funding

MRC, Wellcome Trust, BBSRC

Collaborations

At the University of Bristol, UK:

Teaching

  • Level 1: Techniques in Neuroscience Unit
  • Level 2 : Lectures within the Central Nervous System Unit
  • Level 3: Seminars within the Neural Bases of Learning and Memory Unit
  • Seminars within the Brain Functions and Disorders Unit

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Publications, recommended reading and further information

Warburton,EC, Koder,TJ, Cho,K, Massey,PV, Duguid,GL, Barker,GRI, (Aggleton,J), Bashir,ZI & Brown,MW
Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory
Neuron (2003) 38, 987 - 996

Massey,PV, Warburton,EC, Wynick,D, Brown,MW & Bashir,ZI
Galanin regulates spatial memory but not visual recognition or synaptic plasticity in perirhinal cortex.
Neuropharmacology (2003) 44, 40 - 48

Warburton,EC, (Baird,AL, Morgan,A, Muir,JL & Aggleton,JP)
The cojoint importance of the hippocampus and anterior thalamic nuclei for allocentric spatial learning.
J. Neuroscience (2001) 21, 7323 - 7330

A.Parker, E.Wilding and T.Bussey (eds.)
A role for extra-perirhinal cortices in recognition memory? Evidence from neuronal recording and immunohistochemical imaging studies'
Chapter(s) in The Cognitive Neuroscience of Memory Encoding and Retrieval (2002) , Psychology Press

Anatomy department website
MRC CentreFurther information on the work of the group may be found at the MRC Centre for Synaptic Plasticity website.

Projects -  Diseases -  Processes -  Techniques -  Equipment -  Funding -  Collaborations -  Teaching -  Group members -  Publications & further information

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