Drug treatments for breathing dysrhythmias: out-of-the box thinking
Ana Paula Abdala Sheikh (School of Physiology, Pharmacology & Neuroscience)
C42, Biomedical Sciences Building
Part of the Snapshot seminar series hosted by the School of Physiology, Pharmacology and Neuroscience.
Abstract: With increased life expectancy and high prevalence of obesity in the general population, the incidence of sleep disordered breathing has been increasing. This condition is associated with increased cardiovascular risk and has a negative impact on quality of life and productivity. Despite recent therapeutic success achieved for multiple CNS diseases, drug development attrition rates remain high, and disorders of breathing control remain without pharmacological treatment. I will demonstrate how a deeper understanding of the respiratory circuit oscillator helped us depart from traditional drug development strategies, to discover novel unexpected therapeutic targets for control of breathing.
For further information contact Alex Conibear.