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Details for Professor Neil Marrion

Personal details
Name Professor Neil Marrion
Job title Professor of Neuroscience
Department School of Physiology, Pharmacology & Neuroscience University of Bristol
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
Qualifications BSc, PhD(Lond)
Professional details
Membership of professional bodies Society for Neuroscience
Biophysical Society
British Pharmacological Society
Keywords single channel
patch clamp
Alzheimer's disease
muscular dystrophy
Areas of expertise The hippocampus is known to play a key role in the consolidation of memory and research has focused on the changes in membrane excitability that occur during the creation of memories. Neuronal excitability is regulated by the activation of both voltage- and calcium-dependent potassium currents. The Marrion laboratory uses a multidisciplinary approach to study how voltage-dependent potassium channels are activated and the functional relationship between ion channel subtypes that controls activation of calcium-activated potassium channels. In addition, the laboratory has pioneered a new technique to resolve the exocytosis of a single vesicle containing neurotransmitter.

The understanding that learning and memory consolidation are controlled by the excitability of the CNS neurons has revolutionized our approach to disease states such as Alzheimer's disease and epilepsy. The Marrion laboratory is contributing to this understanding to permit an appreciation of how these processes are influential in particular CNS disease states.
Media experience I have appeared on the Saturday Breakfast show on BBC Radio Bristol