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Details for Dr Monica Berry

Personal details
Name Dr Monica Berry
Job title Visiting Lecturer
Department School of Physics University of Bristol
Personal web page http://www.bris.ac.uk/nsqi-centre/research/berry.html
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
email:
Qualifications MSc(Tel-Aviv), PhD(Bristol)
Professional details
Membership of professional bodies Biochemical Society
Tear Film and Ocular Surface Society
Keywords mucins
ocular surface
tears
in vitro toxicology
Areas of expertise I am fascinated by the complex interactions that occur in the tears and at the ocular surface. The preocular fluid is organised by long, sugar-rich polymers, called mucins, whose physiology and biophysics I am investigating. Which are the structural characteristics that underpin the many postulated mucin roles at the ocular surface? How do disease-induced changes in, say, polymer length and in the number and nature of sugar chains that decorate it, how do these changes affect the quality of the preocular fluid? How do they affect interactions with bacteria? These are a few of the questions to which we are finding answers.

Another main research interest is developing in vitro toxicology tests that are mechanistically linked to ocular surface physiology. Towards assessing the effects of mild and moderate toxicants we have evolved a 3D construct that comprises a stratified epithelium and a stromal-cells populated collagen gel.
Languages (other than English)
Hebrew spoken    written
Romanian spoken    written
French spoken