Genetics of Complex Traits and Diseases: David Evans

Programme Overview

Common diseases typically have complex etiologies and are a result of a myriad of different genetic and environmental factors acting and interacting together to increase or decrease risk of disease. Our group uses techniques including next generation sequencing and micro-array genotyping in conjunction with statistical methods such as genome-wide association and Mendelian Randomization to understand the genetic and environmental causes of complex traits and diseases. We have a particular interest in osteoporosis (thinning of the bones), immunological diseases such as eczema and ankylosing spondylitis (a form of auto-immune arthritis), and how early life factors might increase risk of disease later in life. We are also active in the development of statistical methodologies for detecting disease genes and for investigating possible causal relationships between modifiable environmental exposures and complex disease.

In this group

Research Highlights

Dr David Evans
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