News in 2017

  • David Telling Grant 11 December 2017 Enhanced PPAR-delta expression in patients with periodontitis promotes the inflammatory and pro-atherosclerotic properties of monocytes/macrophages The most common cause of heart attacks is atherosclerosis.
  • Major funding boost for internationally-recognised healthcare research centres 11 December 2017 Three interdisciplinary research consortia, including the University of Bristol's SPHERE project, have been allocated more than £11 million to continue healthcare sensing systems research that is revolutionising how we identify and respond to outbreaks of infectious diseases, diagnose and manage lung diseases, and recognise and solve emerging health and wellbeing issues in the home environment.
  • Research reveals how cells rebuild after division 4 December 2017 University of Bristol research has revealed how cells rebuild their nucleus and organise their genome when they divide – a discovery which could have major implications for understanding cancer and degeneration.
  • Biology and chemistry combine to generate new antibiotics 28 November 2017 Combining the innovations of synthetic biology with biology and chemistry, a team of scientists at the University of Bristol have generated a brand-new platform that will allow the production of desperately needed brand-new antibiotics.
  • Revolutionary microscope and labelling technique maps DNA mutations 23 November 2017 A team of scientists working at the University of Bristol have developed a new nanomapping microscope - powered by the laser and optics found in a typical DVD player.
  • Breastfed babies are less likely to have eczema as teenagers, study shows 17 November 2017 Babies whose mothers had received support to breastfeed exclusively for a sustained period from birth have a 54 per cent lower risk of eczema at the age of 16, a new study led by researchers from King's College London, Harvard University, University of Bristol and McGill University shows.
  • Category winners to be honoured in Vice-Chancellor’s Impact Awards 17 November 2017 The category winners of this year’s Vice-Chancellor’s Impact Awards, which showcase the diverse and globally important contributions that University of Bristol research makes to society, have been announced.
  • Bristol wins grant to tackle antibacterial drug resistance in Thailand 16 November 2017 The University of Bristol has been awarded a grant through the Antimicrobial Resistance (AMR) cross-research council initiative, in partnership with the Department of Health, to lead an inter-disciplinary research project to tackle the growing threat of antibacterial drug resistance (ABR) in Thailand.
  • Antibiotic Discovery in the Abyss 15 November 2017 Combining the innovations of synthetic biology with robotic environmental sampling, a team of University of Bristol researchers are travelling to some of the most ‘extreme’ environments on Earth, including Atlantic depths of 4.5km, to find new leads which could help in the global fight against antimicrobial resistance.
  • Bristol Vet School leading the way to change antimicrobial (AM) use on farms 14 November 2017 Researchers from the Bristol Veterinary School at the University of Bristol are leading the way to inspire and change antimicrobial (AM) use on farms and in veterinary prescribing practices.
  • Primary care is key to optimising value in healthcare 14 November 2017 Balancing improvements in health against the cost of such improvements in primary care is vital to achieve a cost-effective and efficient healthcare system, finds a new report by University of Bristol researchers and published in the BMJ.
  • New international consortium to accelerate drug discovery in kidney diseases 8 November 2017 A new consortium to accelerate the discovery of novel drugs to treat kidney diseases was announced on Monday, 6 November 2017. The NEPLEX (nephron on a chip with cellular and extracellular matrix complexity) consortium, comprising leading academic institutions including the Universities of Bristol and Cambridge, and Evotec AG, will combine key technologies to develop and build a novel drug discovery device ("Nephron-on-a-Chip").
  • Group B Streptococcus infection causes an estimated 150,000 preventable stillbirths and infant deaths every year 6 November 2017 An estimated one in five pregnant women around the world carry Group B Streptococcus (GBS) bacteria which is a major, yet preventable, cause of maternal and infant ill health globally.
  • Academy of Medical Sciences grant to Dr Sofia Theodoropoulou 2 November 2017 Age-related macular degeneration (AMD) is a leading cause of irreversible blindness. Current treatments are available only for the very late stages of the wet form of AMD (caused by the aberrant growth of new vessels-angiogenesis) and only improve vision in 30% of those patients.
  • A new method for the 3D printing of living artificial tissues 1 November 2017 A team from the University of Bristol’s School of Cellular and Molecular Medicine, together with scientists at the University of Oxford, has developed a new method to 3D-print stem cells to form complex living 3D structures.
  • Key discoveries offer significant hope of reversing antibiotic resistance 30 October 2017 Two recent studies led by the University of Bristol provide significant new hope in the fight against antibiotic resistance. By identifying what makes some bacteria resistant to the most commonly prescribed antibiotics, and how this can be reversed, the findings have demonstrated potentially life-saving consequences and could help reverse the tide of antibiotic resistance.
  • Scientists pinpoint genetic risk factors for asthma, hay fever and eczema 24 October 2017 A major international study has pinpointed more than 100 genetic risk factors that explain why some people suffer from asthma, hay fever and eczema.
  • Substantial investment to tackle challenges of African vector-borne plant diseases 5 October 2017 The University of Bristol has been awarded £2 million to lead a major new project that aims to tackle the devastation caused by vector-borne plant diseases in Africa.
  • Bristol to lead national PhD training programme to tackle antimicrobial resistance 28 September 2017 In response to the urgent and global threat of antimicrobial resistance (AMR), the Medical Research Foundation (MRF), the charitable foundation of the Medical Research Council, has invested £2.85M in delivering the UK’s first nationwide PhD training programme to focus on this major health challenge.
  • Interventions for reducing hepatitis C infection in people who inject drugs 26 September 2017 The first global review to quantify the impact of needle syringe programmes (NSP) and opioid substitution treatment (OST) in reducing the risk of becoming infected with the hepatitis C virus is published in Cochrane Library Drug and Alcohol Review Group and the journal Addiction. The study, has implications for millions of people who are 'at risk' from infection.
  • New study aims to find the best moisturiser for treating eczema in children 22 September 2017 Researchers at the Universities of Bristol, Nottingham and Southampton have been awarded £1.4 million by the National Institute for Health Research (NIHR) Health Technology Assessment Programme to discover which is the best emollient (moisturiser) for treating childhood eczema.
  • Study investigating effectiveness of The Lightning Process® programme to treat children with mild or moderate CFS or ME finds symptoms improve 21 September 2017 The first trial to investigate The Lightning Process® (LP) has been published in the Archives of Disease in Childhood. In this trial, the effectiveness of LP in addition to specialist medical care was compared to specialist medical care alone in children with mild or moderate chronic fatigue syndrome (also known as myalgic encephalomyelitis, CFS/ME).
  • Surprising discovery - how the African tsetse fly really drinks your blood 21 September 2017 Researchers at the University of Bristol have been taking a close-up look at the biting mouthparts of the African tsetse fly as part of ongoing work on the animal diseases it carries.
  • RCGP Research Paper of the Year award for CAPC-led study on urinary infections in children 18 September 2017 Research that helps GPs identify urinary tract infections in young children has been awarded a 2017 Royal College of General Practitioners (RCGP) Research Paper of the Year award.
  • How are antimicrobials used around the world in food-producing animals? 4 September 2017 A new study led by academics at the Bristol Veterinary School has reviewed the literature on the use of antimicrobials (AM) in livestock practice together with the views of stakeholders. The study found that although there are some barriers to change, there is a clear awareness of the issue among the livestock sectors and a willingness to modify AM use.
  • Steroids not effective for chest infections in adults who don’t have asthma or other chronic lung disease 22 August 2017 Oral steroids should not be used for treating acute lower respiratory tract infection (or ‘chest infections’) in adults who don’t have asthma or other chronic lung disease, as they do not reduce the duration or severity of symptoms, according to a new study published in the journal JAMA [22 August].
  • Bristol scientists to study oral bacteria that cause heart valve infection 21 August 2017 Scientists at the University of Bristol are investigating how bacteria in our mouth can cause a heart problem, called infective endocarditis. Although uncommon, infective endocarditis is a serious condition that can often be fatal.
  • University of Bristol team develop a new test to assist GP antibiotic prescribing 3 August 2017 A research team at the University of Bristol has won a prestigious international award for a technology that could help in the fight against antibiotic resistance.
  • WUN Strategic Research Workshop 1 August 2017 The World Universities Network Global Africa Group launched its inaugural Strategic Research Workshop, hosted by the University of Ghana in a two-day event that brought together over sixty researchers from twelve WUN partner universities and ten other universities from four continents.
  • Structure of newly discovered antibiotics finally pinned down 1 August 2017 Chemists from the University of Bristol have revised the structure of baulamycins A and B by combining chemical synthesis, computational modelling and Nuclear Magnetic Resonance (NMR) spectroscopy.
  • Adrenal gland activity change under severe stress causing abnormal release of glucocorticoid stress hormones 27 July 2017 To respond to stress optimally, the body needs to produce glucocorticoid hormones, such as cortisol, extremely quickly. New research by scientists from the Universities of Bristol and Exeter has revealed the molecular network that enables rapid glucocorticoid production within the adrenal glands, and has shown how the behaviour of this network can be altered under severe stress.
  • Transforming UK Translation commitments 27 July 2017 The Academy of Medical Sciences, Royal Academy of Engineering, Royal Society, and the Wellcome Trust, have outlined a series of commitments to ensure that translation is recognised and celebrated as an integral part of academic research.
  • How can diagnostics deliver a more effective use of antibiotics in animals? 12 July 2017 Are there better ways to diagnose animals in need of antibiotics on livestock farms? How will farmers and veterinarians use novel diagnostics in the fight against animal disease? These are some questions a consortium of seven academics – including two veterinarians from the University of Bristol's School of Veterinary Sciences - will address thanks to a £1.75 million grant to understand how better diagnostics can encourage responsible antibiotic use in animals.
  • New trial for prosthetic hip joint infection 28 June 2017 The first ever randomised trial to investigate why some patients develop infections after their hip or knee replacement surgery, and which type of surgical revision treatment is best is being run by the University of Bristol and members of the public are being asked to consider taking part.
  • Preventing progression in diabetic kidney disease 13 June 2017 Glitazones are drugs used to treat type 2 diabetes because they improve insulin resistance and reduce progression of associated kidney disease. But how do they work? The EBI’s Clinical Primer scheme for early-career clinicians has allowed a Bristol-based clinician, Dr Caroline Platt, to explore this question.
  • Informatics service support for health and biomedical research at the University of Bristol 13 June 2017 The Elizabeth Blackwell Institute for Health Research (EBI), through its Wellcome Trust ISSF Award, and match funded by the University of Bristol, invested in two posts that are openly available to help support all health and biomedical researchers across the University in their informatics needs.
  • Novel targeting of disease causing cells could transform treatment of autoimmune diseases 24 May 2017 There is a problem with the traditional treatment of autoimmune and inflammatory conditions. Steroid therapy doesn’t always work, and immunosuppressant drugs can have toxic side effects. Bristol researchers, with the help of an award from the Elizabeth Blackwell Institute, are working to overcome this using novel ways of targeting disease causing cells.
  • Achievements of the Chronic Kidney Disease HIT in 2016-17 23 May 2017 One in ten people live with chronic kidney disease (CKD). This is a long-term condition that can increase the risk of heart disease or a sudden deterioration in kidney function, also known as acute kidney injury. The Chronic Kidney Disease Health Integration Team (CKD HIT) is a team of clinical staff and patients, working together to improve patient outcomes and care pathways for patients with kidney disease.
  • Bristol Bones and Joints highlights for 2016-17 23 May 2017 The Bones and Joints HIT covers three disease areas: osteoarthritis, osteoporosis and inflammatory rheumatological disorders, underpinned by three themes of patient self-management, patient and public involvement and information technology.
  • Bristol Immunisation Group’s highlights for 2016-17 23 May 2017 The Bristol Immunisation Group brings public health, clinical and academic experts together to improve the local performance and resilience of the national immunisation programmes. We also work to develop and deliver improvements through innovation and research.
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